CRISPR/Cas9 RNP System Shown to Be Effective for Gene Editing in Epidermolysis Bullosa Mice
Researchers have successfully applied the CRISPR/Cas9 system in a mouse model of recessive dystrophic epidermolysis bullosa (RDEB) to restore collagen VII protein function, a new study shows. RDEB is caused by mutations in the Col7a1 gene, which leads to either a lack of collagen VII or dysfunctional collagen VII protein. The…