Blocking the Notch signaling pathway — key to cell-to-cell communication — was found to significantly ease signs of fibrosis, or…
Articles by Lindsey Shapiro, PhD
A gene-editing therapy to inactivate a harmful mutated copy of the KRT14Â gene reversed defects in skin cells taken from a…
A new gene-editing strategy that does not require the use of a virus can effectively correct a COL7A1 gene mutation…
Healiva and C4U will collaborate to develop a next-generation gene editing therapy — focusing on new technology to…
The diabetes medication metformin slowed tumor growth and prolonged survival in a mouse model of aggressive squamous cell carcinoma (SCC),…
A rare case of epidermolysis bullosa acquista (EBA) was found in an older man in France with systemic…
Abeona Therapeutics has been working with the U.S. Food and Drug Administration (FDA) ahead of its planned submission of a…
Airway involvement is a rare but burdensome and life-threatening manifestation of epidermolysis bullosa (EB) that requires prompt and proper…
EB-101, an investigational gene-corrected cell therapy, safely and effectively heals large, chronic wounds and eases pain in people with…
A pilot trial will investigate the effects of antimicrobial spray APR-TD011 on bacterial colonization in the wounds of people with…
Patients with recessive dystrophic epidermolysis bullosa (RDEB) had distinct blood metabolic profiles compared with healthy people, a study showed.
Self-reactive antibodies against the stress-induced heat shock protein 70 (Hsp70) were higher in the blood of patients with epidermolysis…