News

Skin-derived stem cells promoted wound closure in RDEB: Study

Skin-derived stem cells enhanced wound closure in people with recessive dystrophic epidermolysis bullosa (RDEB), according to clinical trial data. The treatment reduced the occurrence of new wounds, extended the time that they recurred, and wounds that did not fully close got smaller. A larger clinical trial using a control…

Phase 2 trial of cannabinol cream INM-755 is fully enrolled

InMed Pharmaceuticals has completed enrollment for a Phase 2 trial testing INM-755, an investigational cannabinol cream, for people with epidermolysis bullosa (EB). “We look forward to the data read-out in the summer, so we can evaluate our strategic options and next steps,” Eric A. Adams, InMed’s president and CEO,…

Companies team up to ID biomarkers for cancer treatment in RDEB

Onconova Therapeutics and Pangea Biomed are teaming up to identify biomarkers that can help predict a response to the experimental cancer therapy rigosertib in people with recessive dystrophic epidermolysis bullosa (RDEB). Multiple clinical trials are underway to test rigosertib — developed by Onconova — as a potential treatment…

30+ conditions more common in EBA patients ID’d in study

People with epidermolysis bullosa acquisita (EBA) are at a higher risk of developing other autoimmune disorders, certain types of cancers, and heart diseases, a study suggests. The findings also indicate that other autoimmune diseases as well as some infections may be risk factors for EBA. The study, “…

Tofacitinib treatment eases man’s EB acquisita symptoms

Tofacitinib, a therapy approved for certain inflammatory diseases effectively controlled symptoms of epidermolysis bullosa acquisita (EBA) in a man with the disease. The case was described as a letter to the editor titled “Treatment of Recurrent Epidermolysis Bullosa Acquisita With Tofacitinib” in JAMA Dermatology. EBA is a…

Case report describes 4 children with EB and airway ills

Airway involvement is a rare but burdensome and life-threatening manifestation of epidermolysis bullosa (EB) that requires prompt and proper management, according to a recent case report. Researchers in Saudi Arabia described four children with EB who were brought to their clinic showing involvement of their larynx, or voice box,…