Author Archives: Patricia Inacio PhD

Stress and ‘Helplessness’ Voiced by EB Caregivers in Taiwan

Family members caring for children with epidermolysis bullosa (EB) report considerable stress, fatigue and feelings of helplessness, and need greater social and financial support, a small Taiwanese study based on interviews with 10 caregivers reports. This need is particularly acute in Taiwan, its researchers note, because that country lacks…

Castle Creek Acquires Fibrocell, Now Leading Development of FCX-007 Gene Therapy for RDEB

Castle Creek Pharmaceutical recently acquired Fibrocell Science and is now leading the development of treatments for epidermolysis bullosa (EB), including the investigational gene therapy FCX-007 for the treatment of recessive dystrophic epidermolysis bullosa (RDEB). The companies had previously established a partnership to develop FCX-007. “Our organizations have a shared…

Next-generation DNA Sequencing Efficiently Identifies Novel Mutation Causing Junctional EB in Newborn

Next-generation sequencing ­­­­— a technique that reads DNA sequences much faster and cheaper than standard approaches ­­­­— successfully identified a novel mutation in the LAMB3 gene in a newborn with junctional epidermolysis bullosa (EB), a case study reports. The study, “Targeted next-generation sequencing identifies a novel mutation of LAMB3 in…